The 53-year-old star of films including Donnie Brasco, Catfight and the remake of Psycho, did not regain consciousness after a car crash on August 5
The news was confirmed by a representative for her family to TMZ, who said in a statement: “We have lost a bright light, a kind and most joyful soul, a loving mother, and a loyal friend.
“Anne will be deeply missed but she lives on through her beautiful sons, her iconic body of work, and her passionate advocacy. Her bravery for always standing in her truth, spreading her message of love and acceptance, will continue to have a lasting impact.”
On Friday afternoon representatives for Heche, 53, confirmed she was “brain dead”, which under California law is the definition of death. It was announced earlier in the day Heche would be taken off of life support. It is understood her heartbeat was being maintained in case appropriate organ donation could take place.
On Friday evening, Heche’s eldest son, Homer, 20, released a statement on behalf of himself and his half-brother, Atlas, 13.
“My brother Atlas and I lost our Mom,” he told People. “
“After six days of almost unbelievable emotional swings, I am left with a deep, wordless sadness. Hopefully my mom is free from pain and beginning to explore what I like to imagine as her eternal freedom.”
He added, “Over those six days, thousands of friends, family, and fans made their hearts known to me. I am grateful for their love, as I am for the support of my Dad, Coley, and my stepmom Alexi who continue to be my rock during this time.”
“Rest In Peace Mom, I love you,” Homer Heche concluded.
Earlier on Friday a friend of the actor, Nancy Davis, wrote on Instagram: “Heaven has a new Angel. My loving, kind, fun, endearing and beautiful friend @anneheche went to heaven. I will miss her terribly and cherish all the beautiful memories we have shared.
“Anne was always the kindest, most thoughtful person who always brought out the best in me … My heart is broken.”
Heche’s former partner, Ellen DeGeneres, wrote on Twitter: “This is a sad day. I’m sending Anne’s children, family and friends all of my love.”
“Rest in Peace now Anne,” tweeted the actor Patricia Arquette. “Anne Heche was a wildly talented actress who endured more horror than anyone should have to,” added the respected film historian Mark Harris on Twitter. Harris linked to a 2009 profile of the actor, which detailed her traumatic childhood. “She deserves to be remembered with compassion.”
Many had hoped Heche would make a recovery after a publicist for the actor reported her in a “stable” condition after crashing her car into a house in Los Angeles on 5 August. Firefighters said she had been speaking to them as she was cut free of the wreckage and taken to hospital.
But the actor shortly afterwards lost consciousness and on 8 August representatives posted an update, saying Heche was in an “extreme critical condition” and had slipped into a coma. On Friday, her family said in a statement that she was not expected to survive and that she was being kept on life support to determine if her organs could be donated.
Heche, an actor of sharp intelligence, rose to prominence in the early 1990s, playing twins on the soap Another World, and with film roles, including as Catherine Keener’s sister in Nicole Holofcener’s debut feature, Walking and Talking.
Her first major role was as Johnny Depp’s girlfriend in gangster drama Donnie Brasco (1997). In the same year she was cast in other enduring titles: political satire Wag the Dog, disaster movie Volcano and slasher classic I Know What You Did Last Summer.